History

History

     The Compton Metabolic Profile (CMP), first introduced in the early 1970's, has traditionally been used in this approach. The original intent of the CMP was to monitor metabolic health of the heard, help diagnose metabolic problems and production diseases, and identify metabolically superior cows. Interpretation issues and a lack of specificity in differentiating normal from problem herds coupled with high inherent costs with little diagnostic returns has limited the application of the CMP test, especially within the United States. Research since the time of CMP development has clarified many metabolic issues of the transition cow and its relationship to the periparturient disease. In concert with this improved understanding of integrated transition metabolism there has been improvement in technical methods to assess metabolic status. Additionally, the shift to increasing herd size and recognition of significant health, production, and economic consequences of periparturient disease has led to renewed interest in a revised metabolic profile application in monitoring transition cow health and disease risk.

Early Publications:

The Compton Metabolic Profile Test.  J. M. Payne. Proc R Soc Med. 1972 Feb;65(2):181-3

The use of a metabolic profile test in dairy herds. J. M. Payne, S. M. Dew, R. Manston, M. Faulks.  Vet Rec. 1970 Aug 8;87(6):150-8

Blood Metabolic Profiles: Their Use and Relation to Nutritional Status of Dairy Cows. A. J. Lee, A. R. Twardock, et al. 1978. J. Dairy. Sci. 61(11):1652-1670

Use and Limitations of profiles in assessing health or nutritional status of dairy herds. R. S. Adams, W. L. Stout, et al. 1978. J. Dairy Sci. 61(11):1671-1679.