Bortree Series: Tony Maurelli
(Uniformed Services University of the Health Sciences)
"Anti-apoptosis in Shigella and Survival in a Host Cell".
| What | Bortree Series |
|---|---|
| When |
Nov 18, 2009 02:30 PM
Nov 18, 2009 03:30 PM
Nov 18, 2009 from 02:30 pm to 03:30 pm |
| Where | 101 ASI |
| Contact Name | Eric Harvill |
| Contact email | harvill@psu.edu |
| Contact Phone | 863-8522 |
| Add event to calendar |
vCal
iCal
|
Tony Maurelli is a professor of microbiology and immunology in the F. Edward Hébert School of Medicine at the Uniformed Services University of the Health Sciences in Bethesda, Maryland. Dr. Maurelli’s major research interest lies in the genetics of bacterial pathogenesis – the genetic nuts and bolts of how bacteria infect humans and make us sick.
Dr. Maurelli’s work has uncovered “antivirulence genes” in Shigella flexneri, a major cause of dysentery and food borne illness. This is an interesting concept: antivirulence genes undermine pathogenicity, so they must be broken or dropped from the genome for a bacterium to take good advantage of a host and cause disease. These genes are a hindrance, so to become an effective pathogen, Shigella must stop using them.
