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Publications

Kalantari P, Narayan V, Henderson AJ, and Prabhu KS (2009) 15-deoxy-PGJ2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. FASEB J. March 19

 Stahle JA, Vunta H, Reddy CC, and Prabhu KS (2009) Regulation of expression of apolipoprotein A-I by selenium status in hepatocytes. Eur. J. Nutr. March 18

 Palempalli UD, Gandhi U, Kalantari P, Vunta H, Arner RJ, Narayan V, Ravindran A, and Prabhu KS (2009). Gambogic acid covalently modifies IkB-kinase-b subunit to mediate suppression of lipopolysaccharide-induced activation of NF-kB in macrophages. Biochem. J. 419 (2): 401-409.

 DeKeyser JG, Stagliano MC, Auerbach SS, Prabhu KS, Jones AD, and Omiecinski CJ (2009) Di(2-ehtylhexyl)phthalate is a highly potent agonist for the human constitutive androstane receptor splice variant, CAR2. Mol. Pharmacol.  Feb 11

 Hendricks III GL, Hadley JA, Krzysik-Walker SM, Prabhu KS, Vasilatos-Younken R, Ramachandran R (2009) Unique profile of chicken adiponectin, a predominantly heavy molecular weight multimer, and relationship to visceral adiposity. Endocrinology. March 19

 Desai A, Konda VR, Darland G, Austin M, Prabhu KS, Bland J, Caroll B, and Tripp ML (2009) META060 inhibits multiple kinases in the NF-kB pathway and suppresses LPS-mediated inflammation in-vitro and in-vivo. Inflamm. Res. January

Kalantari P, Narayan V, Natarajan SK, Muralidhar K, Gandhi UH, Vunta H, Henderson AJ, Prabhu KS. Thioredoxin reductase-1 negatively regulates HIV-1 transactivating protein Tat-dependent transcription in human macrophages. J Biol Chem. 2008 Oct 3. [Epub ahead of print] PMID: 18835810 [PubMed - as supplied by publisher]

Vunta H, Belda BJ, Arner RJ, Channa Reddy C, Vanden Heuvel JP, Sandeep Prabhu K. Selenium attenuates pro-inflammatory gene expression in macrophages. Mol Nutr Food Res. 2008 May 15. [Epub ahead of print] PMID: 18481333 [PubMed - as supplied by publisher]

Chiaro CR, Morales JL, Prabhu KS, Perdew GH. Leukotriene A4 metabolites are endogenous ligands for the Ah receptor.Biochemistry. 2008 Aug 12;47(32):8445-55. Epub 2008 Jul 11.
PMID: 18616291 [PubMed - indexed for MEDLINE]
 
Kalantari P, Vunta H, Palempalli U, Reddy CC, Henderson AJ, Prabhu KS . Nutritional control of HIV-AIDS: A case for selenium. Am. J. Infectious Diseases. 2007  3 (4): 195-201

Vunta H, Davis F, Palempalli UD, Bhat D, Arner RJ, Thompson JT, Peterson DG, Reddy CC, Prabhu KS. The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages.  J Biol Chem. 2007 Jun 22;282(25):17964-73
 
 The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Free Radic Biol Med. 2007 Apr 15;42(8):1155-64. Epub 2007 Jan 8.
PMID: 17382197 [PubMed - indexed for MEDLINE]

Xing G, Hoffart LM, Diao Y, Prabhu KS, Arner RJ, Reddy CC, Krebs C, Bollinger JM Jr. A coupled dinuclear iron cluster that is perturbed by substrate binding in myo-inositol oxygenase. Biochemistry. 2006 May 2;45(17):5393-401.

Xing G, Diao Y, Hoffart LM, Barr EW, Prabhu KS, Arner RJ, Reddy CC, Krebs C, Bollinger JM Jr. Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6130-5. Epub 2006 Apr 10.

Kim DJ, Prabhu KS , Gonzalez FJ, Peters JM. Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

Arner RJ, Prabhu KS , Krishnan V, Johnson MC, Reddy CC. Expression of myo-inositol oxygenase in tissues susceptible to diabetic complications.Biochem Biophys Res Commun. 2006 Jan 20;339(3):816-20. Epub 2005 Nov 28.

Prabhu KS , Arner RJ, Vunta H, Reddy CC. Up-regulation of human myo-inositol oxygenase by hyperosmotic stress in renal proximal tubular epithelial cells. J Biol Chem. 2005 May 20;280(20):19895-901. Epub 2005 Mar 18.

Arner RJ, Prabhu KS , Reddy CC. Molecular cloning, expression, and characterization of myo-inositol oxygenase from mouse, rat, and human kidney. Biochem Biophys Res Commun. 2004 Nov 26;324(4):1386-92.

Prabhu KS , Reddy PV, Jones EC, Liken AD, Reddy CC. Characterization of a class alpha glutathione-S-transferase with glutathione peroxidase activity in human liver microsomes. Arch Biochem Biophys. 2004 Apr 1;424(1):72-80.

Prabhu KS , Reddy PV, Liken AD, Jones EC, Yennawar HP, Reddy CC. Identification, characterization, and properties of a class alpha microsomal glutathione S-transferase. Adv Exp Med Biol. 2003;525:189-92. No abstract available.

Prabhu KS , Zamamiri-Davis F, Stewart JB, Thompson JT, Sordillo LM, Reddy CC. Selenium deficiency increases the expression of inducible nitric oxide synthase in RAW 264.7 macrophages: role of nuclear factor-kappaB in up-regulation. Biochem J. 2002 Aug 15;366(Pt 1):203-9.

Zamamiri-Davis F, Lu Y, Thompson JT, Prabhu KS , Reddy PV, Sordillo LM, Reddy CC. Nuclear factor-kappaB mediates over-expression of cyclooxygenase-2 during activation of RAW 264.7 macrophages in selenium deficiency. Free Radic Biol Med. 2002 May 1;32(9):890-7.

Prabhu KS , Reddy PV, Gumpricht E, Hildenbrandt GR, Scholz RW, Sordillo LM, Reddy CC. Microsomal glutathione S-transferase A1-1 with glutathione peroxidase activity from sheep liver: molecular cloning, expression and characterization. Biochem J. 2001 Dec 1;360(Pt 2):345-54.

Arner RJ, Prabhu KS , Thompson JT, Hildenbrandt GR, Liken AD, Reddy CC. myo-Inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-chiro-inositol. Biochem J. 2001 Dec 1;360(Pt 2):313-20.