CMIID grad student wins fellowship
December 22, 2010
Congratulations to Alexia T. Karanikas, graduate student in Cell and Developmental Biology in the laboratory of Dr. Eric Harvill. She is the American Heart Association Great Rivers Affiliate Predoctoral Fellowship winner "Natural Killer T cells in Bordetella pertussis Immunity"
Virus particle formation influenced by host factors.
December 8, 2010
Researchers in Tony Schmitt's lab have identified two novel virus-host protein interactions that have opposing effects on assembly and release of paramyxoviruses, including PIV5 and mumps virus. One host protein, 14-3-3, was shown to bind viral M proteins and inhibit particle formation, while the other, AmotL1, binds to M protein and enhances particle formation. In the case of AmotL1, the binding interface was exploited as a target for disabling the virus, providing a proof-of-principal that M protein binding interfaces can be targeted for antiviral drug design.
CMIID Faculty Promoted and Tenured
December 8, 2010
Congratulations to CMIID Associate Professor Sandeep Prabhu for recently being promoted and tenured in the Department of Veterinary and Biomedical Sciences.