Immunology and Infectious Disease
Immunology and Infectious Disease researchers working in the Department of Veterinary and Biomedical Sciences at Penn State.
Our mission is to promote interdisciplinary research and education in the areas of Immunology and Infectious Diseases.
Our research focus is on mechanisms of cancer development in squamous epithelia. We focus primarily on the role of Transforming Growth Factor Beta (TGFβ) and its signaling pathway in the regulation of tumor promotion and progression.
The Harvill lab examines the interactions between microbial pathogens and host immunity in the mouse model using bacteria that naturally infect mice and closely related strains that are important human pathogens.
The primary research interest of the group is to understand the targets of vitamin D in the immune system.
We are interested in how cells integrate the different signals they receive and make correct developmental decisions.
Studies in our laboratory are focused around various cellular and molecular mechanisms by which micronutrients such as selenium and other products of natural origin alter the host response and immune function in response to oxidative stress caused by environmental toxicants and pathogens.