Andrew D. Patterson, PhD

  • Tombros Early Career Professor
  • Professor of Molecular Toxicology
  • Professor of Biochemistry & Molecular Biology
Andrew D. Patterson, PhD
322 Life Sciences Bldg
University Park, PA 16802
Work Phone: 814-867-4565

Areas of Expertise

  • Metabolomics
  • Microbiome
  • Drug Metabolism
  • Metabolism
  • Environmental Contaminants

Connect with Andrew D. Patterson, PhD



  1. Research Fellow, National Cancer Institute (NCI), 2006-2011
  2. Pharmacology Research Associate in Training Fellow, National Institute of General Medical Sciences (NIGMS), 2006-2009
  3. PhD, Genetics, Graduate Partnerships Program, NCI and George Washington University, 2006
  4. BS, Microbiology, Penn State University, 1999

Dr. Patterson is an Associate Professor of Molecular Toxicology at the Pennsylvania State University, University Park, PA and is the Scientific Director of Metabolomics. He and his students, postdocs, and collaborators focus on understanding the host-metabolite-microbiota communication network—specifically how the manipulation of gut microbiota by diet and/or xenobiotics impacts host metabolites (e.g., bile acids, short chain fatty acids), their metabolism, and how these co-metabolites interact with host nuclear/soluble receptors (e.g., farnesoid X receptor, aryl hydrocarbon receptor). The lab employs a variety of tools, including NMR- and mass spectrometry-based metabolomics, genomics, and conventional and gnotobiotic transgenic mice, to facilitate its study of these pathways and understand their impact on human health and disease.