Andrew D. Patterson, PhD

The microbiome modulating activity of bile acids.
Gut microbes, Tian, Y, Gui, W, Koo, I, Smith, Philip, Allman, E, Nichols, R, Rimal, B, Cai, J, Liu, Q, Patterson, Andrew, 2020

Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice.
Toxicology, Zhang, L, Rimal, B, Nichols, R, Tian, Y, Smith, Philip, Hatzakis, E, Chang, S, Butenhoff, J, Peters, Jeffrey, Patterson, Andrew, 2020

The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
Scientific reports, Bao, Lei, Festa, Fernanda, Freet, Christopher S., Lee, John P., Hirschler-Laszkiewicz, Iwona M., Chen, Shu jen, Keefer, Kerry A., Wang, Hong Gang, Patterson, Andrew D., Cheung, Joseph Y., Miller, Barbara A., 2019

Specialist and generalist fungal parasites induce distinct biochemical changes in the mandible muscles of their host
International journal of molecular sciences, Zheng, Shanshan, Loreto, Raquel, Smith, Philip, Patterson, Andrew, Hughes, David, Wang, Liande, 2019

Nutrient Sensing in CD11c Cells Alters the Gut Microbiota to Regulate Food Intake and Body Mass
Cell Metabolism, Chagwedera, D. Nyasha, Ang, Qi Yan, Bisanz, Jordan E., Leong, Yew Ann, Ganeshan, Kirthana, Cai, Jingwei, Patterson, Andrew David, Turnbaugh, Peter J., Chawla, Ajay, 2019

Gender differences in phytoestrogens and the relationship with speed of processing in older adults
Nutrients, Alwerdt, Jessie, Patterson, Andrew D., Sliwinski, Martin J., 2019

Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche
Blood Advances, Hao, Siyang, Xiang, Jie, Wu, Dai Chen, Fraser, James W., Ruan, Baiye, Cai, Jingwei, Patterson, Andrew D., Lai, Zhi Chun, Paulson, Robert F., 2019

Evaluating the structural complexity of isomeric bile acids with ion mobility spectrometry
Analytical and Bioanalytical Chemistry, Zheng, Xueyun, Smith, Francesca B., Aly, Noor A., Cai, Jingwei, Smith, Richard D., Patterson, Andrew David, Baker, Erin S., 2019

Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus)
Journal of agricultural and food chemistry, Tian, Yuan, Gui, Wei, Smith, Philip B., Koo, Imhoi, Murray, Iain A., Cantorna, Margherita T., Perdew, Gary H., Patterson, Andrew D., 2019

Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon
Frontiers in immunology, Cantorna, Margherita T., Lin, Yang Ding, Arora, Juhi, Bora, Stephanie, Tian, Yuan, Nichols, Robert G., Patterson, Andrew D., 2019

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
Nature Medicine, Sun, Lulu, Xie, Cen, Wang, Guang, Wu, Yue, Wu, Qing, Wang, Xuemei, Liu, Jia, Deng, Yangyang, Xia, Jialin, Chen, Bo, Zhang, Songyang, Yun, Chuyu, Lian, Guan, Zhang, Xiujuan, Zhang, Heng, Bisson, William H., Shi, Jingmin, Gao, Xiaoxia, Ge, Pupu, Liu, Cuihua, Krausz, Kristopher W., Nichols, Robert G., Cai, Jingwei, Rimal, Bipin, Patterson, Andrew D., Wang, Xian, Gonzalez, Frank J., Jiang, Changtao, 2018

Lipid metabolism and lipophagy in cancer
Biochemical and Biophysical Research Communications, Maan, Meenu, Peters, Jeffrey Maurice, Dutta, Mainak, Patterson, Andrew David, 2018

Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model
Journal of Proteome Research, Allen, Joselyn, Zhang, Jingtao, Quickel, Michael D., Kennett, Mary J., Patterson, Andrew David, Giblin, Pamela Hankey, 2018

Regulation of vitamin D metabolism following disruption of the microbiota using broad spectrum antibiotics
Journal of Nutritional Biochemistry, Bora, Stephanie A., Kennett, Mary J., Smith, Philip B., Patterson, Andrew David, Cantorna, Margherita Teresa-Anna, 2018

Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice
Journal of Functional Foods, Tian, Yuan, Nichols, Robert G., Roy, Pratiti, Gui, Wei, Smith, Philip B., Zhang, Jingtao, Lin, Yangding, Weaver, Veronika, Cai, Jingwei, Patterson, Andrew David, Cantorna, Margherita Teresa-Anna, 2018

Metabolomics Reveals Aryl Hydrocarbon Receptor Activation Induces Liver and Mammary Gland Metabolic Dysfunction in Lactating Mice
Journal of Proteome Research, Belton, Kerry R., Tian, Yuan, Zhang, Limin, Anitha, Mallappa, Smith, Philip B., Perdew, Gary H., Patterson, Andrew David, 2018

Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis
Journal of Nutritional Biochemistry, Tian, Yuan, Nichols, Robert G., Cai, Jingwei, Patterson, Andrew David, Cantorna, Margherita Teresa-Anna, 2018

Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease
Frontiers in immunology, Dey, Adwitia, Allen, Joselyn N., Fraser, James W., Snyder, Lindsay M., Tian, Yuan, Zhang, Limin, Paulson, Robert F., Patterson, Andrew, Cantorna, Margherita T., Hankey-Giblin, Pamela A., 2018

The gut microbiota regulates endocrine vitamin D metabolism through fibroblast growth factor 23
Frontiers in immunology, Bora, Stephanie A., Kennett, Mary J., Smith, Philip B., Patterson, Andrew D., Cantorna, Margherita T., 2018

Attenuation of microbiotal dysbiosis and hypertension in a CRISPR/Cas9 gene ablation rat model of GPER1
Hypertension, Waghulde, Harshal, Cheng, Xi, Galla, Sarah, Mell, Blair, Cai, Jingwei, Pruett-Miller, Shondra M., Vazquez, Guillermo, Patterson, Andrew, Kumar, Matam Vijay, Joe, Bina, 2018

Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis
Nature Medicine, Xie, Cen, Yagai, Tomoki, Luo, Yuhong, Liang, Xianyi, Chen, Tao, Wang, Qiong, Sun, Dongxue, Zhao, Jie, Ramakrishnan, Sadeesh K., Sun, Lulu, Jiang, Chunmei, Xue, Xiang, Tian, Yuan, Krausz, Kristopher W., Patterson, Andrew David, Shah, Yatrik M., Wu, Yue, Jiang, Changtao, Gonzalez, Frank J., 2017

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
Cell Metabolism, Li, Guolin, Xie, Cen, Lu, Siyu, Nichols, Robert G., Tian, Yuan, Li, Licen, Patel, Daxeshkumar, Ma, Yinyan, Brocker, Chad N., Yan, Tingting, Krausz, Kristopher W., Xiang, Rong, Gavrilova, Oksana, Patterson, Andrew David, Gonzalez, Frank J., 2017

Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner
Journal of Functional Foods, Hubbard, Troy D., Murray, Iain Alexander, Nichols, Robert G., Cassel, Kaitlyn, Podolsky, Michael, Kuzu, Guray, Tian, Yuan, Smith, Philip B., Kennett, Mary J., Patterson, Andrew David, Perdew, Gary H., 2017

Orthogonal Comparison of GC-MS and ¹H NMR Spectroscopy for Short Chain Fatty Acid Quantitation
Analytical Chemistry, Cai, Jingwei, Zhang, Jingtao, Tian, Yuan, Zhang, Limin, Hatzakis, Emmanuel, Krausz, Kristopher W., Smith, Philip B., Gonzalez, Frank J., Patterson, Andrew David, 2017

Intestinal Farnesoid X Receptor Signaling Modulates Metabolic Disease
Digestive Diseases, Gonzalez, Frank J., Jiang, Changtao, Xie, Cen, Patterson, Andrew D., 2017

An intestinal farnesoid x receptor-ceramide signaling axis modulates hepatic gluconeogenesis in mice
Diabetes, Xie, Cen, Jiang, Changtao, Shi, Jingmin, Gao, Xiaoxia, Sun, Dongxue, Sun, Lulu, Wang, Ting, Takahashi, Shogo, Anitha, Mallappa, Krausz, Kristopher W., Patterson, Andrew David, Gonzalez, Frank J., 2017

Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice
Journal of Nutritional Biochemistry, Xiao, Xia, Yeoh, Beng San, Saha, Piu, Tian, Yuan, Singh, Vishal, Patterson, Andrew D., Vijay-Kumar, Matam, 2017

Gut microbiota increased by omega-3 fatty acids is negatively correlated with hepatic lipid metabolism-associated genes in mice with high carbohydrate diet-induced steatosis
The FASEB Journal, Huang, Kuan-Hsun, Nichols, Robert, Sebastian, Aswathy, Albert, Istvan, Patterson, Andrew, Ross, A Catharine, None, 2017

Lipid emulsion added to a liquid high-carbohydrate diet and voluntary running exercise reduce lipogenesis and ameliorate early-stage hepatic steatosis in mice
Journal of Nutrition, Huang, Kuan Hsun, Hao, Lei, Smith, Philip B., Rogers, Connie J., Patterson, Andrew D., Ross, A. Catharine, 2017

Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice.
The Journal of nutritional biochemistry, Xiao, X, Yeoh, B, Saha, Piu, Tian, Y, Singh, V, Patterson, Andrew, Vijay-Kumar, M, 2016

Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice
Scientific reports, Murray, Iain A., Nichols, Robert G., Zhang, Limin, Patterson, Andrew D., Perdew, Gary H., 2016

Farnesoid X receptor signaling shapes the gut microbiota and controls hepatic lipid metabolism
mSystems, Zhang, Limin, Xie, Cen, Nichols, Robert G., Chan, Siu H.J., Jiang, Changtao, Hao, Ruixin, Smith, Philip B., Cai, Jingwei, Simons, Margaret N., Hatzakis, Emmanuel, Maranas, Costas D., Gonzalez, Frank J., Patterson, Andrew D., 2016

Perfluorooctane sulfonate-choline ion pair formation
Toxicological Sciences, Zhang, Limin, Krishnan, Prasad, Ehresman, David J., Smith, Philip B., Dutta, Mainak, Bagley, Bradford D., Chang, Shu Ching, Butenhoff, John L., Patterson, Andrew D., Peters, Jeffrey M., 2016

Metabolomics reveals altered lipid metabolism in a mouse model of endometriosis
Journal of Proteome Research, Dutta, Mainak, Anitha, Mallappa, Smith, Philip B., Chiaro, Christopher R., Maan, Meenu, Chaudhury, Koel, Patterson, Andrew David, 2016

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis
Journal of Immunology, Yu, Shan, Allen, Joselyn N., Dey, Adwitia, Zhang, Limin, Balandaram, Gayathri, Kennett, Mary J., Xia, Mingcan, Xiong, Na, Peters, Jeffrey Maurice, Patterson, Andrew David, Giblin, Pamela Hankey, 2016

Mass spectrometry-based metabolomics identifies longitudinal urinary metabolite profiles predictive of radiation-induced cancer
Cancer Research, Cook, John A., Chandramouli, Gadisetti V.R., Anver, Miriam R., Sowers, Anastasia L., Thetford, Angela, Krausz, Kristopher W., Gonzalez, Frank J., Mitchell, James B., Patterson, Andrew D., 2016

Impaired recovery from peritoneal inflammation in a mouse model of mild dietary zinc restriction
Molecular Nutrition and Food Research, Phillips, Brett E., Geletzke, Abby K., Smith, Philip B., Podany, Abigail B., Chacon, Alexander, Kelleher, Shannon L., Patterson, Andrew D., Soybel, David I., 2016

Antioxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota
Journal of Proteome Research, Cai, Jingwei, Zhang, Limin, Jones, Richard A., Correll, Jared B., Hatzakis, Emmanuel, Smith, Philip B., Gonzalez, Frank J., Patterson, Andrew David, 2016

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
Nature communications, Jiang, Changtao, Xie, Cen, Lv, Ying, Li, Jing, Krausz, Kristopher W., Shi, Jingmin, Brocker, Chad N., Desai, Dhimant, Amin, Shantu G., Bisson, William H., Liu, Yulan, Gavrilova, Oksana, Patterson, Andrew D., Gonzalez, Frank J., 2015

Kernel approaches for differential expression analysis of mass spectrometry-based metabolomics data
BMC bioinformatics, Zhan, Xiang, Patterson, Andrew David, Ghosh, Debashis, 2015

Lack of soluble fiber drives diet-induced adiposity in mice
American Journal of Physiology - Gastrointestinal and Liver Physiology, Chassaing, Benoit, Miles-Brown, Jennifer, Pellizzon, Michael, Ulman, Edward, Ricci, Matthew, Zhang, Limin, Patterson, Andrew D., Vijay-Kumar, Matam, Gewirtz, Andrew T., 2015

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
Scientific reports, Hubbard, Troy D., Murray, Iain A., Bisson, William H., Lahoti, Tejas S., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H., 2015

Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice
Environmental Science and Technology, Zhang, Limin, Hatzakis, Emmanuel, Nichols, Robert G., Hao, Ruixin, Correll, Jared, Smith, Philip B., Chiaro, Christopher R., Perdew, Gary H., Patterson, Andrew D., 2015

Persistent organic pollutants modify gut microbiota–host metabolic homeostasis in mice through aryl hydrocarbon receptor activation
Environmental health perspectives, Zhang, Limin, Nichols, Robert G., Correll, Jared, Murray, Iain A., Tanaka, Naoki, Smith, Philip B., Hubbard, Troy D., Sebastian, Aswathy, Albert, Istvan, Hatzakis, Emmanuel, Gonzalez, Frank J., Perdew, Gary H., Patterson, Andrew D., 2015

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet
Biochimica et Biophysica Acta - Molecular Basis of Disease, Tanaka, Naoki, Takahashi, Shogo, Zhang, Yuan, Krausz, Kristopher W., Smith, Philip B., Patterson, Andrew D., Gonzalez, Frank J., 2015

Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity
Journal of Hepatology, Gonzalez, Frank J., Jiang, Changtao, Bisson, William H., Patterson, Andrew David, 2015

Modulation of colon cancer by nutmeg
Journal of Proteome Research, Li, Fei, Yang, Xiu Wei, Krausz, Kristopher W., Nichols, Robert G., Xu, Wei, Patterson, Andrew David, Gonzalez, Frank J., 2015

Quantitative analysis of purine nucleotides indicates that purinosomes increase de Novo purine biosynthesis
Journal of Biological Chemistry, Zhao, Hong, Chiaro, Christopher R., Zhang, Limin, Smith, Philip B., Chan, Chung Yu, Pedley, Anthony M., Pugh, Raymond J., French, Jarrod B., Patterson, Andrew D., Benkovic, Stephen J., 2015

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease
Journal of Clinical Investigation, Jiang, Changtao, Xie, Cen, Li, Fei, Zhang, Limin, Nichols, Robert G., Krausz, Kristopher W., Cai, Jingwei, Qi, Yunpeng, Fang, Zhong Ze, Takahashi, Shogo, Tanaka, Naoki, Desai, Dhimant, Amin, Shantu G., Albert, Istvan, Patterson, Andrew D., Gonzalez, Frank J., 2015

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice
Cell Metabolism, Singh, Vishal, Chassaing, Benoit, Zhang, Limin, San Yeoh, Beng, Xiao, Xia, Kumar, Manish, Baker, Mark T., Cai, Jingwei, Walker, Rachel, Borkowski, Kamil, Harvatine, Kevin J., Singh, Nagendra, Shearer, Gregory C., Ntambi, James M., Joe, Bina, Patterson, Andrew D., Gewirtz, Andrew T., Vijay-Kumar, Matam, 2015

Species-specific ant brain manipulation by a specialized fungal parasite
BMC Evolutionary Biology, De Bekker, Charissa, Quevillon, Lauren E., Smith, Philip B., Fleming, Kimberly R., Ghosh, Debashis, Patterson, Andrew David, Hughes, David Peter, 2014

Identification of serum insulin-like growth factor binding protein 1 as diagnostic biomarker for early-stage alcohol-induced liver disease
Journal of Translational Medicine, Li, Heng Hong, Doiron, Kathryn, Patterson, Andrew D., Gonzalez, Frank J., Fornace, Albert J., 2013

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
Nature communications, Li, Fei, Jiang, Changtao, Krausz, Kristopher W., Li, Yunfei, Albert, Istvan, Hao, Haiping, Fabre, Kristin M., Mitchell, James B., Patterson, Andrew D., Gonzalez, Frank J., 2013

Metabolomics Reveals the Heterogeneous Secretome of Two Entomopathogenic Fungi to Ex Vivo Cultured Insect Tissues
PloS one, de Bekker, Charissa, Smith, Philip B., Patterson, Andrew D., Hughes, David P., 2013

Metabolomics reveals that tumor xenografts induce liver dysfunction
Molecular and Cellular Proteomics, Li, Fei, Patterson, Andrew D., Krausz, Kristopher W., Jiang, Changtao, Bi, Huichang, Sowers, Anastasia L., Cook, John A., Mitchell, James B., Gonzalez, Frank J., 2013

Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity
Chemical Research in Toxicology, Patterson, Andrew David, Carlson, Bradley A., Li, Fei, Bonzo, Jessica A., Yoo, Min Hyuk, Krausz, Kristopher W., Conrad, Marcus, Chen, Chi, Gonzalez, Frank J., Hatfield, Dolph L., 2013

cbiochemistry and physiology of the β class carbonic anhydrase (Cpb) from clostridium perfringens strain 13
Journal of bacteriology, Siva Sai Kumar, R., Hendrick, William, Correll, Jared B., Patterson, Andrew David, Melville, Stephen B., Ferry, James Gregory, 2013

White Button mushrooms increase microbialdiversity and accelerate the resolution of Citrobacter rodentium infection in mice
Journal of Nutrition, Varshney, Jyotika, Ooi, Jot Hui, Jayarao, Bhushan M., Albert, Istvan, Fisher, Jenny, Smith, Rhonda L., Patterson, Andrew D., Cantorna, Margherita T., 2013

Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism
Journal of Proteome Research, Li, Fei, Pang, Xiaoyan, Krausz, Kristopher W., Jiang, Changtao, Chen, Chi, Cook, John A., Krishna, Murali C., Mitchell, James B., Gonzalez, Frank J., Patterson, Andrew David, 2013

Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis
Cell Metabolism, Matsubara, Tsutomu, Tanaka, Naoki, Krausz, Kristopher W., Manna, Soumen K., Kang, Dong Wook, Anderson, Erik R., Luecke, Hans, Patterson, Andrew D., Shah, Yatrik M., Gonzalez, Frank J., 2012

Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier
PLoS Genetics, Menezes, Luis F., Zhou, Fang, Patterson, Andrew D., Piontek, Klaus B., Krausz, Kristopher W., Gonzalez, Frank J., Germino, Gregory G., 2012

Radiation metabolomics. 5. Identification of urinary biomarkers of ionizing radiation exposure in nonhuman primates by mass spectrometry-based metabolomics
Radiation Research, Johnson, Caroline H., Patterson, Andrew David, Krausz, Kristopher W., Kalinich, John F., Tyburski, John B., Kang, Dong Wook, Luecke, Hans, Gonzalez, Frank J., Blakely, William F., Idle, Jeffrey R., 2012

Role of the Ah receptor in homeostatic control of fatty acid synthesis in the liver
Toxicological Sciences, Tanos, Rachel, Murray, Iain A., Smith, Philip B., Patterson, Andrew, Perdew, Gary H., 2012

Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics
American Journal of Clinical Nutrition, Johnson, Caroline H., Slanař, Ondřej, Krausz, Kristopher W., Kang, Dong Wook, Patterson, Andrew David, Kim, Jung Hwan, Luecke, Hans, Gonzalez, Frank J., Idle, Jeffrey R., 2012

Metabolomics reveals an essential role for peroxisome proliferator- activated receptor α in bile acid homeostasis
Journal of Lipid Research, Li, Fei, Patterson, Andrew D., Krausz, Kristopher W., Tanaka, Naoki, Gonzalez, Frank J., 2012

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice
Journal of Biological Chemistry, Zhang, Yuanyuan, Li, Fei, Patterson, Andrew D., Wang, Yao, Krausz, Kristopher W., Neale, Geoffrey, Thomas, Sarah, Nachagari, Deepa, Vogel, Peter, Vore, Mary, Gonzalez, Frank J., Schuetz, John D., 2012

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity
Hepatology, Patterson, Andrew D., Shah, Yatrik M., Matsubara, Tsutomu, Krausz, Kristopher W., Gonzalez, Frank J., 2012

Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis
Hepatology, Tanaka, Naoki, Matsubara, Tsutomu, Krausz, Kristopher W., Patterson, Andrew D., Gonzalez, Frank J., 2012

Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner
Hepatology, Tanos, Rachel, Patel, Rushang D., Murray, Iain Alexander, Smith, Philip B., Patterson, Andrew David, Perdew, Gary H., 2012

Metabolomics reveals the metabolic map of procainamide in humans and mice
Biochemical Pharmacology, Li, Fei, Patterson, Andrew D., Krausz, Kristopher W., Dick, Bernhard, Frey, Felix J., Gonzalez, Frank J., Idle, Jeffrey R., 2012

Xenobiotic metabolomics
Annual Review of Pharmacology and Toxicology, Johnson, Caroline H., Patterson, Andrew D., Idle, Jeffrey R., Gonzalez, Frank J., 2012

Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling
Cancer Research, Patterson, Andrew David, Maurhofer, Olivier, Beyoǧlu, Diren, Lanz, Christian, Krausz, Kristopher W., Pabst, Thomas, Gonzalez, Frank J., Dufour, Jean François, Idle, Jeffrey R., 2011

UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model
Journal of Proteome Research, Manna, Soumen K., Patterson, Andrew David, Yang, Qian, Krausz, Kristopher W., Idle, Jeffrey R., Fornace, Albert J., Gonzalez, Frank J., 2011

A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice
Carcinogenesis, Hollander, M. Christine, Zhou, Xin, Maier, Colleen R., Patterson, Andrew D., Ding, Xinxin, Dennis, Phillip A., 2011

Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus
Journal of Biological Chemistry, Patterson, Andrew D., Bonzo, Jessica A., Li, Fei, Krausz, Kristopher W., Eichler, Gabriel S., Aslam, Sadaf, Tigno, Xenia, Weinstein, John N., Hansen, Barbara C., Idle, Jeffrey R., Gonzalez, Frank J., 2011

A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics
Biochemical Pharmacology, Li, Fei, Patterson, Andrew D., Höfer, Constance C., Krausz, Kristopher W., Gonzalez, Frank J., Idle, Jeffrey R., 2011

Radiation metabolomics. 4. UPLC-ESI-QTOFMS-based metabolomics for urinary biomarker discovery in gamma-irradiated rats
Radiation research, Johnson, Caroline H., Patterson, Andrew D., Krausz, Kristopher W., Lanz, Christian, Kang, Dong Wook, Luecke, Hans, Gonzalez, Frank J., Idle, Jeffrey R., 2011

Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice
Hepatology, Matsubara, Tsutomu, Tanaka, Naoki, Patterson, Andrew D., Cho, Joo Youn, Krausz, Kristopher W., Gonzalez, Frank J., 2011

Metabolomics identifies novel Hnf1α-dependent physiological pathways in vivo
Molecular Endocrinology, Bonzo, Jessica A., Patterson, Andrew David, Krausz, Kristopher W., Gonzalez, Frank J., 2010

Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics
Biochemical Pharmacology, Li, Fei, Patterson, Andrew David, Höfer, Constance C., Krausz, Kristopher W., Gonzalez, Frank J., Idle, Jeffrey R., 2010

Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the ppara -null mouse
Journal of Proteome Research, Manna, Soumen K., Patterson, Andrew David, Yang, Qian, Krausz, Kristopher W., Li, Henghong, Idle, Jeffrey R., Fornace, Albert J., Gonzalez, Frank J., 2010

Detection of radiation-exposure biomarkers by differential mobility prefiltered mass spectrometry (DMS-MS)
International Journal of Mass Spectrometry, Coy, Stephen L., Krylov, Evgeny V., Schneider, Bradley B., Covey, Thomas R., Brenner, David J., Tyburski, John B., Patterson, Andrew David, Krausz, Kris W., Fornace, Albert J., Nazarov, Erkinjon G., 2010

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in alzheimer's disease
Antioxidants and Redox Signaling, Yoo, Min Hyuk, Gu, Xinglong, Xu, Xue Ming, Kim, Jin Young, Carlson, Bradley A., Patterson, Andrew D., Cai, Huaibin, Gladyshev, Vadim N., Hatfield, Dolph L., 2010