Bhuvana Katkere, MD, PhD

Bhuvana Katkere, MD, PhD

  • Assistant Teaching Professor
  • Immunology and Infectious Disease Major Advisor
  • Faculty advisor for Biomedical Sciences Club
126 ASI Building
University Park, PA 16802

Areas of Expertise

  • Immunology, Microbial Diseases
  • Cell Signaling
  • B Cell Biology - B Cell Receptor Mediated Antigen Processing/Presentation
  • Human Diseases and mechanism
  • Human Health
  • Selenium and B cell functions


  • MD, O. O. Bogomolets National Medical University, Kyiv, Ukraine, 2002
  • PhD, Albany Medical College, Albany, NY, 2012

Bhuvana Katkere is an Assistant Teaching Professor in the Department of Veterinary and Biomedical Sciences at the Pennsylvania State University (PSU). Dr. Katkere’s early training began with medical school in O.O. Bogomolets National Medical University, Kyiv, Ukraine. and attained a M.D degree. Dr. Katkere practiced medicine in India for a few years before pursuing a Ph.D in Immunology and Microbial diseases degree in Albany Medical College, Albany, NY. Ph.D was awarded for her work on “Molecular Requisite for B Cell Receptor Ubiquitination”. As a post-doctoral fellow at Penn State University, Dr. Katkere trained with Dr. Girish S. Kirimanjeswara and Dr. Sandeep Prabhu in the area of Redox biology and Selenoproteins with a focus of the effect of Selenium supplementation on B cell Function. Dr. Katkere has been teaching undergraduate students at Penn State along with research.

Courses taught: 

From 2014 to 2023 -->BMB211, MICRB410, VBSC 50, VBSC 211, VBSC 418, VBSC 445, VBSC 130

Selected Publications

Markley RL, Restori KH, Katkere B, Sumner SE, Nicol MJ, Tyryshkina A, Nettleford SK, Williamson DR, Place DE, Dewan KK, Shay AE, Carlson BA, Girirajan S, Prabhu KS, Kirimanjeswara GS. Front Immunol. 2021 Oct 29;12:701341.

Saha P, Xiao X, Yeoh BS, Chen Q, Katkere B, Kirimanjeswara GS, Vijay-Kumar M. Gut Microbes. 2019;10(3):412-423. 

Goralski TD, Dewan KK, Alumasa JN, Avanzato V, Place DE, Markley RL, Katkere B, Rabadi SM, Bakshi CS, Keiler KC, Kirimanjeswara GS.  2016 May 23;60(6):3276-82. 

Katkere, B., Rosa, S., Drake, J. R. J Biol Chem. 2012 May 11;287(20):16636-44.

Katkere, B., Rosa, S., Caballero, A., Repasky, E. A., Drake, J. R. J Immunol. 2010 Nov 1;185(9):5032-9. 

Wilson, J. E., Katkere, B., Drake, J. R. Infect Immun. 2009 Nov;77(11):4953-65. 

Caballero, A., Katkere, B., Wen, X. Y., Nashar, T. O., and Drake, J. R.  Eur J Immunol. 2006 Dec;36(12):3131-45. 

Katkere, B., and Boiko, I. I. Soy as a major source of protein for vegetarians in India. (Ukrainian), 1999  


DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice
Frontiers in Immunology, Persson, Gry, Restori, Katherine H., Emdrup, Julie Hincheli, Schussek, Sophie, Klausen, Michael Schantz, Nicol, McKayla J., Katkere, Bhuvana, Rønø, Birgitte, Kirimanjeswara, Girish, Sørensen, Anders Bundgaard, 2023

Vitamin D and the Ability to Produce 1,25(OH)2D Are Critical for Protection from Viral Infection of the Lungs
Nutrients, Arora, Juhi, Patel, Devanshi, Nicol, McKayla, Field, Cassandra, Restori, Katherine, Wang, Jinpeng, Froelich, Nicole, Katkere, Bhuvana, Terwilliger, Josey, Weaver, Veronika, others, None, Luley, Erin, Kelly, Kathleen, Kirimanjeswara, Girish S., Sutton, Troy, Cantorna, Margherita T., 2022

Macrophage Selenoproteins Restrict Intracellular Replication of Francisella tularensis and Are Essential for Host Immunity
Frontiers in Immunology, Markley, Rachel, Restori, Katherine, Katkere, Bhuvana, Sumner, Sarah, Nicol, McKayla, Tyryshkina, Anastasia, Nettleford, Shaneice, Williamson, David, Place, David, Dewan, Kalyan, Shay, Ashley, others, None, Carlson, Bradley, Girirajan, Santhosh, Prabhu, K. Sandeep, Kirimanjeswara, Girish S., 2021

Selenoproteins Regulate Antigen Processing and Presentation in Antigen Presenting Cells (P24-024-19)
Current Developments in Nutrition, Sumner, Sarah, Katkere, Bhuvana, Nicol, Mckayla, Markley, Rachel, Shay, A, Carlson, Bradley, Prabhu, K, Kirimanjeswara, G, 2019

The bacterial siderophore enterobactin confers survival advantage to Salmonella in macrophages
Gut Microbes, Saha, P, Xiao, Xia, Yeoh, Beng, Chen, Q, Katkere, Bhuvana, Kirimanjeswara, Girish Soorappa, Vijay-Kumar, Matam, 2019

Dual roles of the bacterial siderophore enterobactin by inducing apoptosis in macrophages and promoting survival advantages to Salmonella typhimurium
The Journal of Immunology, Saha, P, Xiao, Xia, Yeoh, Beng, Chen, Q, Katkere, Bhuvana, Kirimanjeswara, G, Vijay-Kumar, Matam, 2018

Development of a novel Francisella tularensis live vaccine strain expressing ovalbumin provides insight into antigen-specific CD8+ T cell responses
PLoS One, Place, David, Williamson, D, Yuzefpolskiy, Yevgeniy, Katkere, Bhuvana, Sarkar, S, Kalia, V, Kirimanjeswara, Girish S., 2017

Selenoproteins regulate B cell receptor-mediated activation and development of B cells, Katkere, Bhuvana, Markley, R, Shay, A, Prabhu, KS, Kirimanjeswara, G, 2016

Inhibitors of ribosome rescue arrest growth of francisella tularensis at all stages of intracellular replication
Antimicrobial Agents and Chemotherapy, Goralski, Tyler, Dewan, Kalyan, Alumasa, John N., Avanzato, Victoria, Place, David, Markley, Rachel, Katkere, Bhuvana, Rabadi, Seham, Bakshi, Chandra, Keiler, Kenneth C., Kirimanjeswara, Girish S., others, None, 2016