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Molly Hall, PhD, M.S.

  • Assistant Professor
  • Dr. Frances Keesler Graham Early Career Professor
Molly Hall, PhD, M.S.
Veterinary and Biomedical Sciences
College of Agricultural Sciences
Huck Institutes of the Life Sciences
512A Wartik Lab
University Park, PA 16802
Work Phone: 814-865-0794

Areas of Expertise

  • Genomics
  • Human Genetics
  • Exposome
  • Genetic Interactions (Epistasis)
  • Gene-Environment Interactions
  • Complex Disease
  • Precision Medicine
  • Biomedical Informatics
  • Metabolomics

Websites

Education

  1. Postdoctoral Fellowship - University of Pennsylvania School of Medicine
  2. PhD - Penn State University, Biochemistry & Molecular Biology
  3. MS - Columbia University, Neuroscience & Education
  4. BS - Cornell University, Human Development

Research:

The Hall Lab is focused on building tools to elucidate the complex genetic and environmental underpinnings of human disease. We integrate genetic (genotype, sequence, structural variation) and exposure (derived from surveys and metabolomics methods) big data to predict disease status. The ultimate goals of this work are to 1) enrich our understanding of the complex mechanisms that lead to common disease and 2) provide methods to identify those most at risk of disease (based on their genetic and exposure backgrounds) in a clinical setting.

 

Select Publications:

Lucas AM, Palmiero NE, McGuigan J, Passero K, Zhou J, Orie D, Ritchie MD and Hall MA (2019) CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits. Front. Genet. 10:1240. doi: 10.3389/fgene.2019.01240 

 

Hall MA, Wallace J, Lucas A, et al. (2017) PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies. Nature Communications: 8 1167

 

Hall MA, Moore JH, Ritchie MD (2016) Embracing complex associations in common traits: Critical considerations for precision medicine. Trends in Genetics: 32, 470-484

 

Hall MA, Verma SS, Wallace J, Lucas A, et al. (2015) Biology-driven gene-gene interaction analysis of age-related cataract in the eMERGE Network. Genetic Epidemiology: 39 376-384

 

Hall MA, Verma A, Brown-Gentry KD, Goodloe R, et al. (2014) Detection of pleiotropy through and phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study. PLoS Genetics: 10.

 

Hall MA, Dudek SM, Goodloe R, Crawford DC, Pendergrass SA, et al. (2014) Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. Pac Symp Biocomput: 200-211

 

 

Research Interests

Molecular Toxicology & Carcinogenesis Research Faculty