Ruth Nissly

Ruth Nissly

  • Assistant Research Professor
Huck Institutes of Life Science
University Park, PA 16802

Dr. Nissly's research centers on understanding factors that enhance or limit viral infections that target mucosal surfaces. This research aims to identify potential therapeutic targets, guide approaches to prophylaxis, and inform early warning systems that flag emerging concerning strains.

Dr. Nissly is a member of Dr. Suresh Kuchipudi's research team. She also manages the Regulatory Virology section of the Animal Diagnostic Laboratory, which focuses on testing for high-consequence pathogens including avian influenza virus.


Impact of an autophagy-inducing peptide on immunogenicity and protection efficacy of an adenovirus-vectored SARS-CoV-2 vaccine
Molecular Therapy - Methods and Clinical Development, Sayedahmed, Ekramy E., Araújo, Marcelo Valdemir, Silva-Pereira, Taiana Tainá, Chothe, Shubhada K., Elkashif, Ahmed, Alhashimi, Marwa, Wang, Wen Chien, Santos, Andrea P., Nair, Meera Surendran, Gontu, Abhinay, Nissly, Ruth, Francisco de Souza Filho, Antônio, Tavares, Mariana Silva, Ayupe, Marina Caçador, Salgado, Caio Loureiro, Donizetti de Oliveira Candido, Érika, Leal Oliveira, Danielle Bruna, Durigon, Edison Luiz, Heinemann, Marcos Bryan, Morais da Fonseca, Denise, Jagannath, Chinnaswamy, Sá Guimarães, Ana Marcia, Kuchipudi, Suresh V., Mittal, Suresh K., 2023

Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance
VirusDisease, Panner Selvam, Manesh Kumar, Kanagaraj, Vijayrani, Kathaperumal, Kumanan, Nissly, Ruth H., Daly, Janet M., Kuchipudi, Suresh V., 2023

Inactivation of HCoV-NL63 and SARS-CoV-2 in aqueous solution by 254 nm UV-C
Journal of Photochemistry and Photobiology B: Biology, Li, Lily X., Nissly, Ruth H., Swaminathan, Anand, Bird, Ian M., Boyle, Nina R., Nair, Meera Surendran, Greenawalt, Denver I., Gontu, Abhinay, Cavener, Victoria S., Sornberger, Ty, Freihaut, James D., Kuchipudi, Suresh V., Bahnfleth, William P., 2023

SARS-CoV-2 Prevalence and Variant Surveillance among Cats in Pittsburgh, Pennsylvania, USA
Viruses, Ramasamy, Santhamani, Gontu, Abhinay, Neerukonda, Sabarinath, Ruggiero, Diana, Morrow, Becky, Gupta, Sheweta, Amirthalingam, Saranya, Hardham, John M., Lizer, Joshua T., Yon, Michele, Nissly, Ruth H., Jakka, Padmaja, Chothe, Shubhada K., LaBella, Lindsey C., Tewari, Deepanker, Nair, Meera Surendran, Kuchipudi, Suresh Varma, 2023

Complete Genome Sequence of a Bovine Coronavirus Isolated from a Goat in Pennsylvania, USA
Genome Announcements, Chothe, Shubhada K., Byukusenge, Maurice, Sekhwal, Manoj K., Li, Lingling, LaBella, Lindsey Cecelia, Jakka, Padmaja, Palchak, Kay, Barry, Rhiannon, Yon, Michele, Nissly, Ruth H., Kelly, Kathleen, Jayarao, Bhushan M., Nair, Meera Surendran, Kuchipudi, Suresh Varma, 2023

Little Brown Bats (Myotis lucifugus) Support the Binding of SARS-CoV-2 Spike and Are Likely Susceptible to SARS-CoV-2 Infection
Viruses, Chothe, Shubhada K., Jakka, Padmaja, Boorla, Veda Sheersh, Ramasamy, Santhamani, Gontu, Abhinay, Nissly, Ruth H., Brown, Justin, Turner, Gregory, Sewall, Brent J., Reeder, Dee Ann M., Field, Kenneth A., Engiles, Julie B., Amirthalingam, Saranya, Ravichandran, Abirami, LaBella, Lindsey, Nair, Meera Surendran, Maranas, Costas D., Kuchipudi, Suresh V., 2023

Optimized conditions for Listeria, Salmonella and Escherichia whole genome sequencing using the Illumina iSeq100 platform with point-and-click bioinformatic analysis
PLoS One, Narvaez, Sonsiray Alvarez, Shen, Zhenyu, Yan, Lifang, Stenger, Brianna L.S., Goodman, Laura B., Lim, Ailam, Nissly, Ruth H., Nair, Meera Surendran, Zhang, Shuping, Sanchez, Susan, 2022

Mitigating the Impact of Emerging Animal Infectious Disease Threats: First Emerging Animal Infectious Diseases Conference (EAIDC) Report
Viruses, Kuchipudi, Suresh V., Behring, Deanna, Nissly, Ruth, Chothe, Shubhada K., Gontu, Abhinay, Ravichandran, Abirami, Butler, Ty, 2022

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
Science advances, Mabrouk, Moustafa T., Chiem, Kevin, Rujas, Edurne, Huang, Wei Chiao, Jahagirdar, Dushyant, Quinn, Breandan, Nair, Meera Surendran, Nissly, Ruth H., Cavener, Victoria S., Boyle, Nina R., Sornberger, Ty A., Kuchipudi, Suresh V., Ortega, Joaquin, Julien, Jean Philippe, Martinez-Sobrido, Luis, Lovell, Jonathan, 2021

Acoustofluidic Fluorescence Activated Cell Sorter
Analytical Chemistry, Nawaz, Ahmad Ahsan, Chen, Yuchao, Nama, Nitesh, Nissly, Ruth Helmus, Ren, Liqiang, Ozcelik, Adem, Wang, Lin, McCoy, J. Philip, Levine, Stewart J., Huang, Tony Jun, 2015

Immunological Analyses of Whole Blood via “Microfluidic Drifting” Based Flow Cytometric Chip
Annals of Biomedical Engineering, Nawaz, Ahmad Ahsan, Nissly, Ruth Helmus, Li, Peng, Chen, Yuchao, Guo, Feng, Li, Sixing, Shariff, Yasir M., Qureshi, Arooj Nawaz, Wang, Lin, Huang, Tony Jun, 2014

Differential analysis of lysed whole blood via "Microfluidic drifting" based flow cytometry chip, Nawaz, Ahmad Ahsan, Nissly, Ruth Helmus, Li, Peng, Shariff, Yasir M., Wang, Lin, Huang, Tony Jun, 2014