Suresh V Kuchipudi, BVSc, MVSc, PhD, FHEA, Diplomate ACVM

Biography

Dr Kuchipudi is a Clinical Professor and serves as the Associate Director of Animal Diagnostic Laboratory (ADL). Dr Kuchipudi is the head of microbiology, overseeing bacteriology, virology, serology and molecular diagnostic units of ADL. He is an American College of Veterinary Microbiologists (ACVM) board certified specialist in virology and immunology. The goal of Dr. Kuchipudi's research is to generate knowledge that can underpin the development of novel diagnostic tools and intervention therapies for endemic and emerging viral diseases of animals and humans. Current research in the Kuchipudi lab involves a range of viruses of veterinary and zoonotic importance. 

Kuchipudi Laboratory

Honorary positions

Adjunct Professor, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu,India

Board Certification

Diplomate, American College of Veterinary Microbiologists (DACVM)

• Virology-2014
• Immunology-2018

• Pathobiology
• Molecular Cellular and Integrative Biosciences (MCIBS)

Teaching  

• VBSC-444- Epidemiology of Infectious Diseases
• VBSC-496- Independent Studies

Professional Memberships

• American College of Veterinary Microbiologists (ACVM)
• American Association of Veterinary Laboratory Diagnosticians (AAVLD)
• American Society for Microbiology (ASM)
• Fellowship of Higher Education academy (HEA), UK

Barry, R., Nissly, R.H., Feria, W., Thirumalapura, N., Tewari, D., Jayarao, B.M. and Kuchipudi, S.V*(2019). A probe based real-time PCR assay for the detection of Neospora caninum in clinical samples from cattle. Veterinary Parasitology, 269:2-6.

Dayakar A, Chandrasekaran S, Kuchipudi SV* and Kalangi SK (2019) Cytokines: Key Determinants of Resistance or Disease Progression in Visceral Leishmaniasis: Opportunities for Novel Diagnostics and Immunotherapy. Front. Immunol. 10:670. doi: 10.3389/fimmu.2019.00670

Byukusenge M, Li L, Uwanyirigira M, Vepachedu VR, Kariyawasam S, Nzayirambaho M, Kuchipudi SV*, Jayarao BM. 2019. Complete genome sequences of 20 nontyphoidal Salmonella isolates from Rwanda. Microbiol Resour Announc 8:e00016-19. https://doi.org/ 10.1128/MRA.00016-19.

Sujit Pujhari, Vanessa M. Macias, Ruth H. Nissly, Masashi Nomura, Suresh V. Kuchipudi and Jason L. Rasgon. 2019. Heat shock protein 70 (Hsp70) co-localizes with Zika virus and is involved in the cellular infection process. Emerging Microbes & Infections, 8:1, 8-16, DOI: 10.1080/22221751.2018.1557988   

Kuchipudi SV* and Nissly R. 2018. Novel Flu Viruses in Bats and Cattle: "Pushing the Envelope" of Influenza Infection. Vet Sci. 2018 Aug 6;5(3). pii: E71. doi: 10.3390/vetsci5030071.

Maurice Byukusenge, Ruth Helmus Nissly, Sunitha Manjari Kasibhatla, Lingling Li, Rebekah Russell, Hayley Springer, Rhiannon Barry, Robert Van Saun, David Wolfgang, Ernest Hovingh, Urmila Kulkarni-Kale, Suresh V. Kuchipudi*.2018. Complete genome sequences of four bovine coronavirus isolates from Pennsylvania. Genome announcements, 6(22).

Shubhada K Chothe, Aswathy Sebastian, Asha Thomas, Ruth Nissly, David Wolfgang, Maurice Byukusenge, Sunil Mor, Sagar Goyal, Istvan Albert, Bhushan Jayarao and Suresh V. Kuchipudi*.2018. Whole-genome sequence analysis reveals unique SNP profiles to distinguish vaccine and wild-type strains of Bovine Herpes Virus-1. Virology, 522, 27-36

Shabbir MZ, Nissly RH, Ahad A, Rabbani M, Chothe SK, Sebastian A, Albert I, Jayarao BM, Kuchipudi SV*. 2018. Complete genome sequences of three related avian avulavirus 1 isolates from poultry farmers in Pakistan. Genome Announc 6:e00361-18. https://doi.org/10.1128/genomeA.00361-18.

Shubhada K. Chothe, Aswathy Sebastian, Asha Thomas, Ruth Nissly, Maurice Byukusenge, David Wolfgang, Sunil Kumar Mor, Sagar Goyal, Istvan Albert, Bhushan Jayarao, and Suresh V. Kuchipudi*. 2018,Whole-Genome Sequences of 18 Bovine Alphaherpesvirus 1 Field Isolates from Pennsylvania and Minnesota, Genome Announc. April 2018; 6:doi:10.1128/genomeA.00294-18

Kay Palchak, Shubhada K. Chothe, Aswathy Sebastian, Ruth H. Nissly, Rhiannon Barry, Istvan Albert, Bhushan M. Jayarao, and Suresh V. Kuchipudi*, 2018, Whole-Genome Sequence of Infectious Pancreatic Necrosis Virus Isolated from Farmed Brook Trout (Salvelinus fontinalis) in Pennsylvania, Genome Announc. April 2018; 6:doi:10.1128/genomeA.00360-18

Vasudevan G, Vanamayya PR, Nagarajan S, Rajukumar K, Suba, S, Venketash G, Tosh C, Sood R, Nissly RH, and Kuchipudi SV*. 2017. Infectious dose-dependent accumulation of live highly pathogenic avian influenza H5N1 virus in chicken skeletal muscle—implications for public health. Zoonoses and Public Health. 2017;00:1–5. https://doi.org/10.1111/zph.12406

Rathnapraba Sambandham, Raja Angamuthu, Vijayarani Kanagaraj, Kumanan Kathaperumal, Shubhada K. Chothe, Ruth H. Nissly, Rhiannon M. Barry, Bhushan M. Jayarao and Suresh V. Kuchipudi*. 2017. An immuno-chromatographic lateral flow assay (LFA) for rapid on-the-farm detection of classical swine fever virus (CSFV). Archives of Virology, DOI 10.1007/s00705-017-3464-4

Shubhada K Chothe, Gitanjali Bhushan, Ruth H. Nissly, Yin-Ting Yeh, Justin Brown, Gregory Turner, Jenny Fisher, Brent J. Sewall, DeeAnn M. Reeder, Mauricio Terrones, Bhushan M Jayarao and Suresh V Kuchipudi*. 2017. Avian and human influenza virus compatible sialic acid receptors in little brown bats. Scientific reports, 7: 660 DOI:10.1038/s41598-017-00793-6

Naveen Gujjar, Shubhada K. Chothe, Shashikant Gawai,Ruth Nissly,Gitanjali Bhushan, Vijayarani Kanagaraj,Bhushan M. Jayarao,Kumanan Kathaperumal, Madhuri Subbiah, and Suresh V. Kuchipudi*.2016. Co-expression of sialic acid receptors compatible with avian and human influenza virus binding in emus (Dromaius novaehollandiae). Virology. Volume 500, January 2017, Pages 114–121, http://dx.doi.org/10.1016/j.virol.2016.10.021 

Chhabra,R., Kuchipudi, S.V., Chantrey, J and Ganapathy, K. 2016. Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses. Virology, Volume 488, 15 January 2016, Pages 232-241

Chothe, S. K., B. M. Jayarao and S. V. Kuchipudi*. 2015. Targeting cellular and virus encoded LncRNAs: Emerging opportunities for novel anti-influenza therapies. British Journal of Virology, 2(6): 102-105.

Chang, P., Kuchipudi, S.V^#., Mellits, K.H., Sebastian, S., James, J., Liu, J., Shelton, H and Chang, K.C. 2015.Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and pro-inflammatory dysregulation. Sci Rep. 2015 Dec 8;5:17999. doi: 10.1038/srep17999.

Sebastian, S., Goulding, L., Kuchipudi, S. V and Chang, K. C. 2015. Extended 2D myotube culture recapitulates postnatal fibre type plasticity.BMC Cell Biol. 2015 Sep 17;16(1):23.

Kuchipudi, S. V.* 2015. The complex role of STAT3 in viral infections. J Immunol Res. Vol. 2015, Article ID 272359, 9 pages, doi:10.1155/2015/272359.

Kuchipudi, S. V.*, Dunham S. P., and Chang, K. C. 2015. DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells. Genomics Data. Vol. 4, June 2015, Pages 60–64, doi:10.1016/j.gdata.2015.03.004, 

Baquero-Perez, B., Kuchipudi, S. V., Ho, J., Sebastian, S., Puranik, A., Howard, W., Brookes, S. M., Brown, I. H., and Chang, K. C. 2015. Chicken and duck myotubes are highly susceptible and permissive to influenza virus infection. J Virol. 89(5):2494-2506. 

Kuchipudi, S. V.* and Chang, K. 2015. Skeletal muscle in influenza virus infection- a key player or a bystander? Brit J Virol. 2(2): 19-21. 

Saravanan, S., Purushothaman, V., Murthy, T., K. Sukumar, P. Srinivasan, V. Gowthaman, M., Balusamy, R., Atterbury, and Kuchipudi, S. V. 2015. Molecular epidemiology of nontyphoidal Salmonella in poultry and poultry products in India: Implications for human health. Indian J Microbiol. 55(3): 319-326. 

Kuchipudi, S. V.*, Tellabati, M., Sebastian, S., Londt, B. Z., Jansen, C., Vervelde, L., Brookes, S. M., Brown, I. H., Dunham, S. P., and Chang K. C. 2014. Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses. Vet Res. 45:118. 

Seng, L. G., Daly, J., Chang K. C., and Kuchipudi, S. V.* 2014. High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance. PLoS ONE. 9(10): e109023. doi:10.1371/journal.pone.0109023.

Roychoudhury, P., Sarma, D. K., Rajkhowa, S., and Kuchipudi, S. V.* 2014. Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in north-eastern region of India. Transbound and Emerg Dis. Aug; 61 Suppl s1:69-77.

Arumugam, U., Vijayarani, K., Kumanan, K., Bhuvaneswari, S., Kuchipudi, S. V., and Elankumaran, S. 2014. Complete genome sequence of a velogenic Nnwcastle disease virus isolated from an apparently healthy village chicken in South India. Genome Announc. May/Jun 19;2(3).

Kuchipudi, S. V*., Tellabati, M., Nelli, R. K., White, G. A., Baquero-Perez, B., Sebastian, S., Slomka, M. J., Brookes, S. M., Brown, I. H., Dunham, S. P. and Chang, K. C. 2012. 18S rRNA is a reliable normalisation gene for real time PCR derived from influenza virus infected cells. Virol J. 9:230.

Kuchipudi, S. V., Dunham, S. P., Nelli, R. K., White, G. A., Perez, B. B., Brown, I., and Chang, K. C. 2012. Rapid death of duck cells infected with Influenza A: a mechanism for host resistance to H5N1. Immunol Cell Biol. 90:116-123.

Nelli, R. K., Dunham, S. P., Kuchipudi, S. V., White, G. A., Baquero-Perez, B., Chang, P., Ghaemmaghami, A., Brookes, S. M., Brown, I. H., and Chang, K. C. 2012. Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced pro-inflammation and infectious virus release. J Virol. 86: 9201-9210.

Baquero-Perez, B., Kuchipudi, S. V., Nelli, R. K., and Chang, K. C. 2012. A simplified but robust method for the isolation of avian and mammalian muscle satellite cells. BMC Cell Biol. 13:16.

Alkurashi, M., Eastick, F. A., Kuchipudi, S. V., Rauch, C., Madouasse, A., Zhu, X. Q., and Elsheikha, H. M. 2011. Influence of culture medium pH on internalization, growth and phenotypic plasticity of Neospora caninum, Vet Parasitol. Vol. 177, no. 3-4, pp. 267-274.

Nelli, R. K., Kuchipudi, S. V., White, G. A., Perez, B. B., Dunham, S. P. and Chang, K. C. 2010.Comparative distribution of human and avian type sialic acid influenza receptors in the pig. BMC Vet.Res. 6:4.

Kuchipudi, S. V., Nelli, R., White, G. A., Bain, M., Chang, K. C., and Dunham, S. 2009. Differences in influenza virus receptors in chickens and ducks: Implications for interspecies transmission. J Mol Genet Med. Vol. 3, no. 1, pp. 143-151.

*Corresponding author.

# Equal contribution.

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Center for Infectious Disease Dynamics

Molecular, Cellular and Integrative Bio-sciences

Animal Diagnostics Research Faculty

Center for Research on Advanced Fiber Technologies (CRAFT)