Troy Sutton, PhD

Defining the transmissible dose 50%, the donor inoculation dose that results in airborne transmission to 50% of contacts, for two pandemic influenza viruses in ferrets
bioRxiv, Field, C., Septer, K.M., Patel, D.R., Weaver, V.C, Sim, D.G., Restori, R., Sutton, Troy, 2025

Pandemic risk stemming from the bovine H5N1 outbreak: an account of the knowns and unknowns.
Journal of virology, Lowen, A, Baker, A, Bowman, A, García-Sastre, A, Hensley, S, Lakdawala, S, Moncla, L, Nelson, M, Pekosz, A, Poulson, R, Puryear, W, Runstadler, J, Sutton, Troy, Tompkins, S, Webby, R, 2025

Vaccine-induced NA immunity decreases viral shedding, but does not disrupt chains of airborne transmission for the 2009 pandemic H1N1 virus in ferrets
mBio, Septer, K. M., Heinly, T. A., Sim, D. G., Patel, D. R., Roder, A. E., Wang, W., Chung, M., Johnson, K. E.E., Ghedin, E., Sutton, Troy, 2024

Defining the Role of Mutations Linked to Transmission of H7N9 Viruses in Ferrets.
Proceedings of NIAID Centers of Excellence for Influenza Research and Response 3rd Annual Conference, Patel, Devanshi, Sutton, Troy, 2024

Pre-existing immunity to seasonal influenza viruses reduces the severity of H5N1 infection in ferrets.
Proceedings of NIAID Centers of Excellence for Influenza Research and Response 3nd Annual Conference, Restori, K, Sutton, Troy, 2024

Combined immunity to hemagglutinin and neuraminidase induced by vaccination or infection results in additive reductions in airborne transmission of the 2009 pandemic H1N1 virus in ferrets
Proceedings of NIAID Centers of Excellence for Influenza Research and Response 3rd Annual Conference, Septer, K, Heinly, T, Sim, D, Patel, D, Roder, A, Wang, W, Chung, M, Johnson KEE, None, Ghedin, E, Sutton, Troy, 2024

Risk assessment of a highly pathogenic H5N1 influenza virus from mink
Nature Communications, Restori, Katherine H., Septer, Kayla M., Field, Cassandra J., Patel, Devanshi R., VanInsberghe, David, Raghunathan, Vedhika, Lowen, Anice C., Sutton, Troy C., 2024

Intranasal SARS-CoV-2 RBD decorated nanoparticle vaccine enhances viral clearance in the Syrian hamster model
Microbiology spectrum, Patel, Devanshi R., Minns, Allen M., Sim, Derek G., Field, Cassandra J., Kerr, Abigail E., Heinly, Talia A., Luley, Erin H., Rossi, Randall M., Bator, Carol M., Moustafa, Ibrahim M., Norton, Elizabeth B., Hafenstein, Susan L., Lindner, Scott E., Sutton, Troy C., 2024

Characterization of Mutations Enriched During Sequential Transmission of H7N9 Influenza Virus in Ferrets
Proceedings of NIAID Centers of Excellence for Influenza Research and Response 2nd Annual Conference, Sutton, Troy, 2023

Virology under the Microscope—a Call for Rational Discourse
Journal of Virology, Goodrum, F, Lowen, A, Lakdawala, S, Alwine, J, Casadevall, A, Imperiale, M, Atwood, W, Avgousti, D, Baines, J, Banfield, B, Banks, L, Bhaduri-McIntosh, S, Bhattacharya, D, Blanco-Melo, D, Bloom, D, Boon, A, Boulant, S, Brandt, C, Broadbent, A, Brooke, C, Cameron, C, Campos, S, Caposio, P, Chan, G, Cliffe, A, Coffin, J, Collins, K, Damania, B, Daugherty, M, Debbink, K, DeCaprio, J, Dermody, T, Dikeakos, J, DiMaio, D, Dinglasan, R, Duprex, W, Dutch, R, Elde, N, Emerman, M, Enquist, L, Fane, B, Fernandez-Sesma, A, Flenniken, M, Frappier, L, Frieman, M, Frueh, K, Gack, M, Gaglia, M, Gallagher, T, Galloway, D, García-Sastre, A, Geballe, A, Glaunsinger, B, Goff, S, Greninger, A, Hancock, M, Harris, E, Heaton, N, Heise, M, Heldwein, E, Hogue, B, Horner, S, Hutchinson, E, Hyser, J, Jackson, W, Kalejta, R, Kamil, J, Karst, S, Kirchhoff, F, Knipe, D, Kowalik, T, Lagunoff, M, Laimins, L, Langlois, R, Lauring, A, Lee, B, Leib, D, Liu, S, Longnecker, R, Lopez, C, Luftig, M, Lund, J, Manicassamy, B, McFadden, G, McIntosh, M, Mehle, A, Miller, W, Mohr, I, Moody, C, Moorman, N, Moscona, A, Mounce, B, Munger, J, Münger, K, Murphy, E, Naghavi, M, Nelson, J, Neufeldt, C, Nikolich, J, O'Connor, C, Ono, A, Orenstein, W, Ornelles, D, Ou, J, Parker, J, Parrish, C, Pekosz, A, Pellett, P, Pfeiffer, J, Plemper, R, Polyak, S, Purdy, J, Pyeon, D, Quinones-Mateu, M, Renne, R, Rice, C, Schoggins, J, Roller, R, Russell, C, Sandri-Goldin, R, Sapp, M, Schang, L, Schmid, S, Schultz-Cherry, S, Semler, B, Shenk, T, Silvestri, G, Simon, V, Smith, G, Smith, J, Spindler, K, Stanifer, M, Subbarao, K, Sundquist, W, Suthar, M, Sutton, Troy, Tai, A, Tarakanova, V, tenOever, B, Tibbetts, S, Tompkins, S, Toth, Z, van Doorslaer, K, Vignuzzi, M, Wallace, N, Walsh, D, Weekes, M, Weinberg, J, Weitzman, M, Weller, S, Whelan, S, White, E, Williams, B, Wobus, C, Wong, S, Yurochko, A, 2023

Virology under the Microscope—a Call for Rational Discourse
mSphere, Goodrum, F, Lowen, A, Lakdawala, S, Alwine, J, Casadevall, A, Imperiale, M, Atwood, W, Avgousti, D, Baines, J, Banfield, B, Banks, L, Bhaduri-McIntosh, S, Bhattacharya, D, Blanco-Melo, D, Bloom, D, Boon, A, Boulant, S, Brandt, C, Broadbent, A, Brooke, C, Cameron, C, Campos, S, Caposio, P, Chan, G, Cliffe, A, Coffin, J, Collins, K, Damania, B, Daugherty, M, Debbink, K, DeCaprio, J, Dermody, T, Dikeakos, J, DiMaio, D, Dinglasan, R, Duprex, W, Dutch, R, Elde, N, Emerman, M, Enquist, L, Fane, B, Fernandez-Sesma, A, Flenniken, M, Frappier, L, Frieman, M, Frueh, K, Gack, M, Gaglia, M, Gallagher, T, Galloway, D, García-Sastre, A, Geballe, A, Glaunsinger, B, Goff, S, Greninger, A, Hancock, M, Harris, E, Heaton, N, Heise, M, Heldwein, E, Hogue, B, Horner, S, Hutchinson, E, Hyser, J, Jackson, W, Kalejta, R, Kamil, J, Karst, S, Kirchhoff, F, Knipe, D, Kowalik, T, Lagunoff, M, Laimins, L, Langlois, R, Lauring, A, Lee, B, Leib, D, Liu, S, Longnecker, R, Lopez, C, Luftig, M, Lund, J, Manicassamy, B, McFadden, G, McIntosh, M, Mehle, A, Miller, W, Mohr, I, Moody, C, Moorman, N, Moscona, A, Mounce, B, Munger, J, Münger, K, Murphy, E, Naghavi, M, Nelson, J, Neufeldt, C, Nikolich, J, O'Connor, C, Ono, A, Orenstein, W, Ornelles, D, Ou, J, Parker, J, Parrish, C, Pekosz, A, Pellett, P, Pfeiffer, J, Plemper, R, Polyak, S, Purdy, J, Pyeon, D, Quinones-Mateu, M, Renne, R, Rice, C, Schoggins, J, Roller, R, Russell, C, Sandri-Goldin, R, Sapp, M, Schang, L, Schmid, S, Schultz-Cherry, S, Semler, B, Shenk, T, Silvestri, G, Simon, V, Smith, G, Smith, J, Spindler, K, Stanifer, M, Subbarao, K, Sundquist, W, Suthar, M, Sutton, Troy, Tai, A, Tarakanova, V, tenOever, B, Tibbetts, S, Tompkins, S, Toth, Z, van Doorslaer, K, Vignuzzi, M, Wallace, N, Walsh, D, Weekes, M, Weinberg, J, Weitzman, M, Weller, S, Whelan, S, White, E, Williams, B, Wobus, C, Wong, S, Yurochko, A, 2023

Virology under the Microscope-a Call for Rational Discourse
mBio, Goodrum, F, Lowen, A, Lakdawala, S, Alwine, J, Casadevall, A, Imperiale, M, Atwood, W, Avgousti, D, Baines, J, Banfield, B, Banks, L, Bhaduri-McIntosh, S, Bhattacharya, D, Blanco-Melo, D, Bloom, D, Boon, A, Boulant, S, Brandt, C, Broadbent, A, Brooke, C, Cameron, C, Campos, S, Caposio, P, Chan, G, Cliffe, A, Coffin, J, Collins, K, Damania, B, Daugherty, M, Debbink, K, DeCaprio, J, Dermody, T, Dikeakos, J, DiMaio, D, Dinglasan, R, Duprex, W, Dutch, R, Elde, N, Emerman, M, Enquist, L, Fane, B, Fernandez-Sesma, A, Flenniken, M, Frappier, L, Frieman, M, Frueh, K, Gack, M, Gaglia, M, Gallagher, T, Galloway, D, García-Sastre, A, Geballe, A, Glaunsinger, B, Goff, S, Greninger, A, Hancock, M, Harris, E, Heaton, N, Heise, M, Heldwein, E, Hogue, B, Horner, S, Hutchinson, E, Hyser, J, Jackson, W, Kalejta, R, Kamil, J, Karst, S, Kirchhoff, F, Knipe, D, Kowalik, T, Lagunoff, M, Laimins, L, Langlois, R, Lauring, A, Lee, B, Leib, D, Liu, S, Longnecker, R, Lopez, C, Luftig, M, Lund, J, Manicassamy, B, McFadden, G, McIntosh, M, Mehle, A, Miller, W, Mohr, I, Moody, C, Moorman, N, Moscona, A, Mounce, B, Munger, J, Münger, K, Murphy, E, Naghavi, M, Nelson, J, Neufeldt, C, Nikolich, J, O'Connor, C, Ono, A, Orenstein, W, Ornelles, D, Ou, J, Parker, J, Parrish, C, Pekosz, A, Pellett, P, Pfeiffer, J, Plemper, R, Polyak, S, Purdy, J, Pyeon, D, Quinones-Mateu, M, Renne, R, Rice, C, Schoggins, J, Roller, R, Russell, C, Sandri-Goldin, R, Sapp, M, Schang, L, Schmid, S, Schultz-Cherry, S, Semler, B, Shenk, T, Silvestri, G, Simon, V, Smith, G, Smith, J, Spindler, K, Stanifer, M, Subbarao, K, Sundquist, W, Suthar, M, Sutton, Troy, Tai, A, Tarakanova, V, tenOever, B, Tibbetts, S, Tompkins, S, Toth, Z, van Doorslaer, K, Vignuzzi, M, Wallace, N, Walsh, D, Weekes, M, Weinberg, J, Weitzman, M, Weller, S, Whelan, S, White, E, Williams, B, Wobus, C, Wong, S, Yurochko, A, 2023

Sequential Transmission of Influenza Viruses in Ferrets Does Not Enhance Infectivity and Does Not Predict Transmissibility in Humans
mBio, Sutton, Troy C., Lamirande, Elaine W., Patel, Devanshi R., Johnson, Katherine E.E., Czako, Rita, Ghedin, Elodie, Lee, Raphael T.C., Maurer-Stroh, Sebastian, Subbarao, Kanta, 2022

Transmission of Human Influenza A Virus in Pigs Selects for Adaptive Mutations on the HA Gene
Journal of Virology, Mo, Jong Suk, Abente, Eugenio J., Perez, Matias Cardenas, Sutton, Troy C., Cowan, Brianna, Ferreri, Lucas M., Geiger, Ginger, Gauger, Phillip C., Perez, Daniel R., Vincent Baker, Amy L., Rajao, Daniela S., 2022

Changes in the Hemagglutinin and Internal Gene Segments Were Needed for Human Seasonal H3 Influenza A Virus to Efficiently Infect and Replicate in Swine
Pathogens, Rajao, Daniela S., Abente, Eugenio J., Powell, Joshua D., Bolton, Marcus J., Gauger, Phillip C., Arruda, Bailey, Anderson, Tavis K., Sutton, Troy C., Perez, Daniel R., Vincent Baker, Amy L., 2022

Defining the relationship between inoculation dose and transmission for the 2009 H1N1 and 1968 H3N2 pandemic influenza viruses, Septer, Kayla, Field, Cassandra, Patel, Devanshi, Sim, D, Sutton, Troy, 2022

Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters., Field, Cassandra, Heinly, Talia, Patel, Devanshi, Sim, D, Luley, Erin, Gupta, S, Vanderford, Thomas, Wrammert, Jens, Sutton, Troy, 2022

The role of vaccine-induced intranasal immunity on transmission of pandemic H1N1 in the ferret model., Septer, Kayla, Sim, D, Patel, Devanshi, Field, Cassandra, Heinly, Talia, Norton, Elizabeth, Sutton, Troy, 2022

Aerosolized Hydrogen Peroxide Decontamination of N95 Respirators, with Fit-Testing and Viral Inactivation, Demonstrates Feasibility for Reuse during the COVID-19 Pandemic
mSphere, Derr, Thomas, James, Melissa, Kuny, Chad, Patel, Devanshi, Kendell, Prem, Kandel, Prem, Field, Cassandra, Beckman, Matthew, Hockett, Kevin L., Bates, Mark, Sutton, Troy, Szpara, Moriah L., 2022

Robustness of the Ferret Model for Influenza Risk Assessment Studies: a Cross-Laboratory Exercise
mBio, Belser, Jessica A., Lau, Eric H.Y., Barclay, Wendy, Barr, Ian G., Chen, Hualan, Fouchier, Ron A.M., Hatta, Masato, Herfst, Sander, Kawaoka, Yoshihiro, Lakdawala, Seema S., Yi Yang Lee, Leo, Neumann, Gabriele, Peiris, Malik, Perez, Daniel R., Russell, Charles, Subbarao, Kanta, Sutton, Troy C., Webby, Richard J., Yang, Huanliang, Yen, Hui Ling, 2022

Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters., Field, Cassandra, Heinly, Talia, Patel, Devanshi, Sim, D, Luley, Erin, Gupta, S, Vanderford, Thomas, Wrammert, Jens, Sutton, Troy, 2022

Intranasal vaccination with hemagglutinin or neuraminidase reduces airborne transmission of pandemic H1N1 in ferrets, Septer, Kayla, Sim, D, Patel, Devanshi, Field, Cassandra, Heinly, Talia, Sutton, Troy, 2022

Vitamin D and the Ability to Produce 1,25(OH)₂D Are Critical for Protection from Viral Infection of the Lungs
Nutrients, Arora, Juhi, Patel, Devanshi, Nicol, McKayla, Field, Cassandra, Restori, Katherine, Wang, Jinpeng, Froelich, Nicole, Katkere, Bhuvana, Terwilliger, Josey, Weaver, Veronika, others, None, Luley, Erin, Kelly, Kathleen, Kirimanjeswara, Girish S., Sutton, Troy, Cantorna, Margherita T., 2022

Immune durability and protection against SARS-CoV-2 re-infection in Syrian hamsters
Emerging Microbes and Infections, Field, C, Heinly, T, Patel, D, Sim, D. G., Luley, E., Gupta, S, Vanderford, T, Wrammert, J, Sutton, T. C., 2022

Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
Journal of Virology, Patel, Devanshi, Field, Cassandra, Septer, Kayla, Sim, Derek G., Jones, Matthew J., Heinly, T, Vanderford, Thomas, McGraw, Elizabeth A., Sutton, Troy, 2021

Development of a swine RNA polymerase I driven Influenza reverse genetics system for the rescue of type A and B Influenza viruses
Journal of Virological Methods, Seibert, Brittany, Angel, Matthew, Caceres, C. Joaquin, Sutton, Troy, Kumar, Ayush, Ferreri, Lucas, Cardenas-Garcia, Stivalis, Geiger, Ginger, Rajao, Daniela, Perez, Daniel R., 2021

A Global Cross-laboratory Exercise to Improve Standardization of Ferret Transmission Studies, Besler, Jessica, Yen, Hui-Ling, Septer, Kayla, Sim, D, Sutton, Troy, 2021

Anti-N1 antibodies induced by intramuscular vaccination do not block airborne transmission of pandemic H1N1 influenza A in ferrets, Septer, Kayla, Sim, D, Patel, Devanshi, Field, Cassandra, Heinly, Talia, Sutton, Troy, 2021

Anti-N1 antibodies induced by intramuscular vaccination do not block airborne transmission of pandemic H1N1 influenza A in ferrets, Septer, Kayla, Patel, Devanshi, Sutton, Troy, 2020

Sequential Airborne Transmission of Influenza Viruses in Ferrets: A Potential Strategy to Evaluate Vaccine Efficacy, Sutton, Troy, Czako, Rita, Lamirande, Elaine, Joseph, Renuka, Subbarao, Kanta, 2018

The pandemic threat of emerging H5 and H7 avian influenza viruses
Viruses, Sutton, Troy C., 2018

Homologous and heterologous protection against influenza B virus following live attenuated influenza virus (LAIV) immunization.
Journal of Immunology, Santos, J, Finch, C, Sutton, Troy, Obadan, A, Aguirre, I, Wan, Z, Lopez, D, Gieger, G, Gonzalez, A, Ferreri, L, Perez, D, 2018

H5N2 vaccine viruses on Russian and US live attenuated influenza virus backbones demonstrate similar infectivity, immunogenicity and protection in ferrets
Vaccine, Czakó, Rita, Vogel, Leatrice, Sutton, Troy, Matsuoka, Yumiko, Krammer, Florian, Chen, Zhongying, Jin, Hong, Subbarao, Kanta, 2018

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
npj Vaccines, Sutton, Troy C., Chakraborty, Saborni, Mallajosyula, Vamsee V.A., Lamirande, Elaine W., Ganti, Ketaki, Bock, Kevin W., Moore, Ian N., Varadarajan, Raghavan, Subbarao, Kanta, 2017

In vitro neutralization is not predictive of prophylactic efficacy of broadly neutralizing monoclonal antibodies CR6261 and CR9114 against lethal H2 influenza virus challenge in mice
Journal of Virology, Sutton, Troy C., Lamirande, Elaine W., Bock, Kevin W., Moore, Ian N., Koudstaal, Wouter, Rehman, Muniza, Weverling, Gerrit Jan, Goudsmit, Jaap, Subbarao, Kanta, 2017

Evaluation of the biological properties and cross-reactive antibody response to h10 influenza viruses in ferrets
Journal of Virology, Sutton, Troy C., Lamirande, Elaine W., Czako, Rita, Subbarao, Kanta, 2017

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody
PLoS Pathogens, Houser, Katherine V., Broadbent, Andrew J., Gretebeck, Lisa, Vogel, Leatrice, Lamirande, Elaine W., Sutton, Troy, Bock, Kevin W., Minai, Mahnaz, Orandle, Marlene, Moore, Ian N., Subbarao, Kanta, 2017

Seasonal, Pandemic, and Emerging Influenza Viruses Transmit with Similar Efficiency Over Sequential Rounds of Airborne Contact in Ferrets, Sutton, Troy, Czako, Rita, Lamirande, Elaine, Joseph, Renuka, Subbarao, Kanta, 2017

Development of an alternative modified live influenza B virus vaccine
Journal of Virology, Santos, Jefferson J.S., Finch, Courtney, Sutton, Troy, Obadan, Adebimpe, Aguirre, Isabel, Wan, Zhimin, Lopez, Diego, Geiger, Ginger, Gonzalez-Reiche, Ana Silvia, Ferreri, Lucas, Perez, Daniel R., 2017

Induction of protective immunity against influenza A/Jiangxi-Donghu/346/2013 (H10N8) in mice
Journal of General Virology, Kuah, Li Fang, Tang, Lay Hoon, Sutton, Troy, Lim, Jie Hui, Sin, Wan Ling, Lamirande, Elaine, Subbarao, Kanta, Lau, Yuk Fai, 2017

Evaluation of replication and cross-reactive antibody response of twenty H10 influenza viruses in ferrets, Sutton, Troy, Lamirande, Elaine, Subbarao, Kanta, 2016

Bacterially expressed influenza group 2 hemagglutinin stem-immunogen vaccines protect mice from lethal challenge, Sutton, Troy, Mallajosyula, V, Lamirande, Elaine, Varadarajan, Raghavan, Subbarao, Kanta, 2016

Prophylaxis with broadly neutralizing monoclonal antibodies CR6261 and CR9114 protects mice against lethal H2 influenza virus challenge., Sutton, Troy, Lamirande, E, Rehman, M, Weverling, G, Goudsmit, J, Subbarao, Kanta, 2015

Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus
Virology, Sutton, Troy C., Subbarao, Kanta, 2015

Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States
Journal of Virology, Rajão, D, Gauger, P, Anderson, T, Lewis, N, Abente, E, Killian, M, Perez, D, Sutton, Troy, Zhang, J, Vincent, A, 2015