Vanessa "Sue" Wacleche, PhD

  • IID Faculty
  • Veterinary and Biomedical Sciences
439 Shortlidge Road
AVBS Building

University Park, PA 16802

Publications

Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
Nature, Law, Calvin, Wacleche, Vanessa Sue, Cao, Ye, Pillai, Arundhati, Sowerby, John, Hancock, Brandon, Horisberger, Alice, Bracero, Sabrina, Skidanova, Viktoriya, Li, Zhihan, Adejoorin, Ifeoluwakiisi, Dillon, Eilish, Benque, Isaac J., Nunez, Diana Pena, Simmons, Daimon P., Keegan, Joshua, Chen, Lin, Baker, Tina, Brohawn, Phillip Z., Al-Mossawi, Hussein, Hao, Ling Yang, Jones, Brian, Rao, Navin, Qu, Yujie, Alves, Stephen E., Albrecht, Jennifer, Anolik, Jennifer H., Apruzzese, William, Barnas, Jennifer L., Bathon, Joan M., Ben-Artzi, Ami, Boyce, Brendan F., Boyle, David L., Bridges, S. Louis, Bykerk, Vivian P., Campbell, Debbie, Ceponis, Arnold, Chicoine, Adam, Curtis, Michelle, Deane, Kevin D., DiCarlo, Edward, Donlin, Laura T., Dunn, Patrick, Filer, Andrew, Carr, Hayley, Firestein, Gary S., Forbess, Lindsy, Geraldino-Pardilla, Laura, Goodman, Susan M., Gravallese, Ellen M., 2024

Young researchers series #4
Trends in Cell Biology, Smith, Keisha, Green, Mykel D., Wacleche, Vanessa Sue, 2022

Identification of T Peripheral Helper (Tph) Cells, Wacleche, Vanessa S., Wang, Runci, Rao, Deepak A., 2022

Raldh activity induced by bacterial/fungal pathogens in cd16+ monocyte-derived dendritic cells boosts hiv infection and outgrowth in cd4+ t cells
Journal of Immunology, Cattin, Amelie, Wacleche, Vanessa Sue, Do Rosario, Natalia Fonseca, Marchand, Laurence Raymond, Dias, Jonathan, Gosselin, Annie, Cohen, Eric A., Estaquier, Jerome, Chomont, Nicolas, Routy, Jean Pierre, Ancuta, Petronela, 2021

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid
Frontiers in Microbiology, Zhang, Yuwei, Planas, Delphine, Raymond Marchand, Laurence, Massanella, Marta, Chen, Huicheng, Wacleche, Vanessa Sue, Gosselin, Annie, Goulet, Jean Philippe, Filion, Mario, Routy, Jean Pierre, Chomont, Nicolas, Ancuta, Petronela, 2020

PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21
JCI insight, Bocharnikov, Alexandra V., Keegan, Joshua, Wacleche, Vanessa S., Cao, Ye, Fonseka, Chamith Y., Wang, Guoxing, Muise, Eric S., Zhang, Kelvin X., Arazi, Arnon, Keras, Gregory, Li, Zhihan J., Qu, Yujie, Gurish, Michael F., Petri, Michelle, Buyon, Jill P., Putterman, Chaim, Wofsy, David, James, Judith A., Guthridge, Joel M., Diamond, Betty, Anolik, Jennifer H., Mackey, Matthew F., Alves, Stephen E., Nigrovic, Peter A., Costenbader, Karen H., Brenner, Michael B., Lederer, James A., Rao, Deepak A., 2019

CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features
Blood advances, Wacleche, Vanessa Sue, Cattin, Aḿelie, Goulet, Jean Philippe, Gauchat, Dominique, Gosselin, Annie, Cleret-Buhot, Auŕelie, Zhang, Yuwei, Tremblay, Ćecile L., Routy, Jean Pierre, Ancuta, Petronela, 2018

The biology of monocytes and dendritic cells: Contribution to HIV pathogenesis
Viruses, Wacleche, Vanessa Sue, Tremblay, Cécile L., Routy, Jean Pierre, Ancuta, Petronela, 2018

The Th17 lineage: From barrier surfaces homeostasis to autoimmunity, cancer, and HIV-1 pathogenesis
Viruses, Wacleche, Vanessa Sue, Landay, Alan, Routy, Jean Pierre, Ancuta, Petronela, 2017

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy
AIDS, Gosselin, Annie, Salinas, Tomas Raul Wiche, Planas, Delphine, Wacleche, Vanessa S., Zhang, Yuwei, Fromentin, Remi, Chomont, Nicolas, Cohen, Eric A., Shacklett, Barbara, Mehraj, Vikram, Ghali, Maged P., Routy, Jean Pierre, Ancuta, Petronela, 2017

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy
Retrovirology, Wacleche, Vanessa Sue, Goulet, Jean Philippe, Gosselin, Annie, Monteiro, Patricia, Soudeyns, Hugo, Fromentin, Rémi, Jenabian, Mohammad Ali, Vartanian, Shant, Deeks, Steven G., Chomont, Nicolas, Routy, Jean Pierre, Ancuta, Petronela, 2016

Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach
Retrovirology, Cleret-Buhot, Aurélie, Zhang, Yuwei, Planas, Delphine, Goulet, Jean Philippe, Monteiro, Patricia, Gosselin, Annie, Wacleche, Vanessa Sue, Tremblay, Cécile L., Jenabian, Mohammad Ali, Routy, Jean Pierre, El-Far, Mohamed, Chomont, Nicolas, Haddad, Elias K., Sekaly, Rafick Pierre, Ancuta, Petronela, 2015

Impaired Th17 polarization of phenotypically naive CD4+ T-cells during chronic HIV-1 infection and potential restoration with early ART
Retrovirology, DaFonseca, Sandrina, Niessl, Julia, Pouvreau, Sylvia, Wacleche, Sue V., Gosselin, Annie, Cleret-Buhot, Aurélie, Bernard, Nicole, Tremblay, Cécile, Jenabian, Mohammad Ali, Routy, Jean Pierre, Ancuta, Petronela, 2015