"Bioenergetics of Clostridium Difficile: Relationships to Pathogenesis and Drug Discovery Potential""

William Self Burnett School of Biomedical Sciences University of Central Florida

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September 21, 2016, 11:00 AM - 12:00 PM

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Bill Self is an Associate Professor in the Burnett School of Biomedical Sciences Bill received his Bachelor of Science in Microbiology with high honors from the University of Florida in 1993, followed by his Ph.D. in 1998 in which he studied the role of molybdenum in the transcriptional regulation of genes involved in energy metabolism in Escherichia coli under Dr. Keelnatham Shanmugam, an expert in microbial physiology and genetics. He then moved on to the National Heart, Lung and Blood Institute under the guidance of Dr. Thressa C. Stadtman at the NIH in Bethesda, Maryland where he studied anaerobic microbiology and biochemistry to help build a solid foundation for future independent research. Since arriving at UCF in 2003 he has continued studies of metalloenzymes from clostridia, especially Clostridium difficile, and also expanded to study newly identified catalytic antioxidant nanomaterials (cerium oxide nanoparticles) in collaboration with Dr. Sudipta Seal. His primary interests in bacteriology include bioenergetics of anaerobes while thriving in the host. He has published over 60 research articles and this work has been highly cited in recent years (H-index of 32 with over 3800 citations, Google Scholar). He has given 12 invited talks at national/international conferences and Universities in the past 7 years, served as a panel chair twice at international conferences and served on ten NIH study sections and five NSF study sections since 2009. He has been awarded four patents and has four pending. Besides his extensive research and service to the profession, Dr. Self has also been heavily involved in service to UCF, including serving four years as a faculty senator, serving as Chair of the undergraduate council for two years and serving on the senate steering committee for three years. Dr. Self also served as a provost faculty fellow this past year under Dale Whittaker. He and his wife of 21 years, Marianne, also spend quite a bit of time raising their four teenage sons. They especially like spending time outdoors boating, fishing and snorkeling in the Keys.

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