The Bortree Lecture Series is a program offered by the Department of Veterinary and Biomedical Sciences that invites distinguished Life Science researchers to present their findings to Penn State students and faculty.
The series can be taken for credit, but is also open to anyone else who would like to attend. The presentations are free to the public, and are usually accompanied by department-sponsored lunches for further discussion with the presenters.
When
April 28, 2021, 12:00 PM - 1:00 PM
Where Zoom https://psu.zoom.us/j/97518265280
Assessing the molecular component of biological samples in situ by mass spectrometry (molecular histology) is a rapidly developing technique. Much of the recent improvement has been due to the synergistic benefits and complementary nature of DESI (Desorption Electrospray) and MALDI (Matrix Assisted Laser Desorption) ionization coupled with high resolution mass spectrometry and ion mobility separation. Types of experiments that benefit from this technique are drug distribution and metabolism, lipid profiling, and biomarker identification, each of which are performed directly from sectioned biological and tissue samples. This discussion will highlight examples of these analyses as well as developments in sampling technology and data management that make real results readily available.
