"The Type I Interferon Family: Only Antivirals? Or Master Regulations of the Immune Response?"
Date and Location
When (Date/Time)February 22, 2017, 11:00 AM - 12:00 PM
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I became interested in immunology very early on and was a student in one of the only two undergraduate Immunology degrees in the world at Glasgow University, Scotland. From there I moved to do my Ph.D with Colin Watts at the University of Dundee, where I worked on non-classical modes of endocytosis, and their role in delivery of exogenous antigen into the MHC Class I pathway during cross presentation. I continued in a similar theme as a post-doc, working with Jon Yewdell and Jack Bennink at NIAID on the NIH Campus in Bethesda. There I worked in the Laboratory of Viral Diseases, which has a heavy emphasis upon poxvirology, and I became interested in the pathogenesis of virus infection, and the balance between the immune response, virus replication and the resulting tissue damage. I continued this work after moving to the Dept. of Microbiology and Immunology at Penn State Hershey in 2002, where I am now a Professor. My current interests are broadly centered around the steps involved in early sensing of virus infection, and the effector mechanisms that control virus spread from a peripheral site of infection.